Artvigil (armodafinil) is a wakefulness-promoting agent for oral administration. Armodafinil is the R-enantiomer of modafinil which is a 1:1 mixture of the R- and S-enantiomers. The chemical name for armodafinil is 2-[(R)-(diphenylmethyl)sulfinyl]acetamide. The molecular formula is C15H15NO2S and the molecular weight is 273.35.

The chemical structure is: Armodafinil is a white to off-white, crystalline powder that is slightly soluble in water, sparingly soluble in acetone, and soluble in methanol.

Uses: Artvigil is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD).

Limitations of Use: In OSA, Artvigil is indicated to treat excessive sleepiness and not as treatment for the underlying obstruction. If continuous positive airway pressure (CPAP) is the treatment of choice for a patient, a maximal effort to treat with CPAP for an adequate period of time should be made prior to initiating Artvigil for excessive sleepiness.

Dapoxetine is a medication used to treat males for sexual dysfunction, such as premature ejaculation. It is also an antidepressant drug. You can also use this with or without alternatives like Kegel exercises, a balanced and healthy diet, and regular exercises. Decreasing your alcohol intake and ceasing of smoking of tobacco could also help in treating this condition.

Mesterolone is an orally active androgeic steriod (AAS) and a dehydro derivative of testosterone (DHT) that is the male sex hormone. It is a weak androgen and is used in the treatment of hypogonadism in men, that is a condition where the testes is not able to produce enough testosterone. It is also used by bodybuliders to temporarily improve vascularity and to maintain libido off cycle.

Artmizol (anastrozole) tablets for oral administration contain 1 mg of anastrozole, a non-steroidal aromatase inhibitor. It is chemically described as 1,3-Benzenediacetonitrile, a, a, a’, a’-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl). Its molecular formula is C17H19N5

The chemical structure is: Artmizol is an off-white powder with a molecular weight of 293.4. Artmizol has moderate aqueous solubility (0.5 mg/mL at 25°C); solubility is independent of pH in the physiological range. Artmizol is freely soluble in methanol, acetone, ethanol, and tetrahydrofuran, and very soluble in acetonitrile.

Uses: RIMIDEX is indicated for adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer.
ARIMIDEX is indicated for the first-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer. ARIMIDEX is indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy. Patients with ER-negative disease and patients who did not respond to previous tamoxifen therapy rarely responded to ARIMIDEX.

Zitafen (tamoxifen citrate) Tablets, a nonsteroidal antiestrogen, are for oral administration.Chemically, Zitafen (tamoxifen citrate) is the trans-isomer of a triphenylethylene derivative. The chemical name is (Z)2-[4-(1,2-diphenyl-1-butenyl) phenoxy]-N, N-dimethylethanamine 2 hydroxy-1,2,3- propanetricarboxylate (1:1).

The chemical structure is: Tamoxifen citrate has a molecular weight of 563.62, the pKa’ is 8.85, the equilibrium solubility in water at 37°C is 0.5 mg/mL and in 0.02 N HCl at 37°C, it is 0.2 mg/mL.

Uses: Metastatic Breast Cancer, Adjuvant Treatment of Breast Cancer. Ductal Carcinoma in Situ (DCIS), Reduction in Breast Cancer Incidence in High Risk Women

Femozole tablets for oral administration contains 2.5 mg of letrozole, a nonsteroidal aromatase inhibitor (inhibitor of estrogen synthesis). It is chemically described as 4,4′-(1H-1,2,4-Triazol-1-ylmethylene) dibenzonitrile. Letrozole is a white to yellowish crystalline powder, practically odorless, freely soluble in dichloromethane, slightly soluble in ethanol, and practically insoluble in water. It has a molecular weight of 285.31, empirical formula C17H11N5, and a melting range of 184°C to 185°C.

Uses: Adjuvant Treatment Of Early Breast Cancer, Extended Adjuvant Treatment Of Early Breast Cancer, First And Second-Line Treatment Of Advanced Breast Cancer.

Clomirate (clomiphene citrate tablets USP) is an orally administered, nonsteroidal, ovulatory stimulant designated chemically as 2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy] triethylamine citrate (1:1). It has the molecular formula of C26H28ClNO • C6H8O7 and a molecular weight of 598.09.

The chemical structure is: Clomiphene citrate is a white to pale yellow, essentially odorless, crystalline powder. It is freely soluble in methanol; soluble in ethanol; slightly soluble in acetone, water, and chloroform; and insoluble in ether.

Uses: Clomirate is indicated for the treatment of ovulatory dysfunction in women desiring pregnancy. Impediments to achieving pregnancy must be excluded or adequately treated before beginning Clomirate therapy. Those patients most likely to achieve success with clomiphene therapy include patients with polycystic ovary syndrome

WARNINGS: Ovarian Hyperstimulation Syndrome), amenorrhea-galactorrhea syndrome, psychogenic amenorrhea, post-oral-contraceptive amenorrhea, and certain cases of secondary amenorrhea of undetermined etiology.